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| Boxer cardiomyopathy ： ウィキペディア英語版 |
Boxer cardiomyopathy
Boxer cardiomyopathy (also known as "Boxer arrhythmogenic right ventricular cardiomyopathy") is a disease of the myocardium primarily affecting Boxer dogs. It is characterized by the development of ventricular tachyarrhythmias, resulting in syncope and sudden cardiac death. Myocardial failure and congestive heart failure are uncommon manifestations of the disease.〔Basso C, Fox PR, Meurs KM, et al. Arrhythmogenic right ventricular cardiomyopathy causing sudden cardiac death in Boxer dogs: A new animal model of human disease. Circulation 2004;109:1180–1185〕
==Overview==
Boxer cardiomyopathy shares striking similarities to a human myocardial disease called arrhythmogenic right ventricular cardiomyopathy (ARVC).〔 On histopathology, the disease is characterized by the progressive replacement of ventricular myocardium (primarily right ventricular myocardium) with fatty or fibro-fatty tissue.〔Meurs KM. Boxer dog cardiomyopathy: An update. Vet Clin North Am Small Anim Pract 2004;34:1235–1244.〕 Clinically, the disease is characterized by the development of ventricular tachyarrhythmias, including ventricular tachycardia and ventricular fibrillation. Affected dogs are at risk of syncope and sudden cardiac death.〔
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